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Albert Henry
I am a research officer at the Garvan Institute of Medical Research, Australia and a honorary research fellow at Insitute of Cardiovascular Science, University College London (UCL), UK. Previously, I was a research fellow at Institute of Health Informatics UCL. I hold a medical doctor degree (general practice) in Indonesia, an MSc degree in Health and Biomedical Data Science, and a PhD in Cardiovascular Genetics. My research combines data science, human genetics, cellular genomics, and stem cell technologies to identify causal biology and inform drug target identification within the field of cardiovascular diseases.
Education
20232018
PhD, Cardiovascular Genetics
Institute of Cardiovascular Science University College London, UK- Thesis: Understanding heart failure using human genetics
20172016
MSc, Data Science for Research in Health and Biomedicine
Institute of Health Informatics University College London, UK- Dissertation: A Mendelian randomization study investigating the causal association between sleep duration and cognitive functions
- Graduated with distincition
- Listed in Faculty Dean’s List of Top Performing Students
20142007
MD
Diponegoro University Semarang, Indonesia- Graduated cum laude
Professional Experience
current2024
Research officer
Garvan Institute of Medical Research NSW, Australiacurrent2024
Honorary research fellow
Institute of Cardiovascular Science University College London, UK20242022
Research fellow
Institute of Health Informatics University College London, UK- Built a high-throughput computational pipeline and led the analysis for drug target validation in cardiovascular diseases by combining large-scale genomics, proteomics, and cardiac magnetic resonance imaging data as part of industry-academia partnership with Pfizer Innovative Target Exploration Network (ITEN) and supported by the British Heart Foundation Research Accelerator Award
20222022
Visiting scientist
Broad Institute of MIT and Harvard Cambridge, MA, USA- Visiting scientist at the Broad Institute Precision Cardiology Laboratory
- Research project: Functional profiling of genomic loci for heart failure with singe-nuclei RNA sequencing
2018
Research assistant
Institute of Health Informatics University College London, UK- Performed statistical analysis, data visualisation, and prepared manuscript for genome-wide association study meta-analysis of heart failure
2016
Laboratory intern
Center for Biomedical Research Semarang, Indonesia- Performed DNA extraction and cytogenetic analysis
2015
General practitioner
Puskesmas (public health centre) Ambarawa Ambarawa, Indonesia- Carried out GP services and health promotion programmes
2014
Emergency room doctor
RSUD (district hospital) Ambarawa Ambarawa, Indonesia- Carried out emergency clinical services
2013
Visiting medical student
Radboud University Nijmegen, The Netherlands- Studied Neglected Tropical Disease and International Public Health
Teaching Experience
20222020
Advanced Statistical Analysis & Advance Statistics in Records Research
Institute of Health Informatics University College London, UK- Developed teaching materials and lectured in risk prediction & Messy Data Challenge
- Online slides: https:
/ / ihi ‑risk ‑teaching .netlify .app /
20222021
Computational Genetics in Healthcare
Institute of Health Informatics University College London, UK- Developed practical materials and served as teaching assistants.
- Topics include Mendelian randomization, GWAS, Polygenic Risk Score, Rare-variant association analysis, and GWAS meta-analysis
20222021
Computational Methods in Biodiversity Research
Department of Genetics, Evolution and Environment University College London, UK- Served as teaching assistants in introduction to data science and statistics with R
2020
Introduction to data visualisation with R
Code Club University College London, UK- Developed materials and delivered an online workshop to visualize Covid-19 case rate with R and ggplot2
- Material: https:
/ / github .com /IHI ‑Code ‑Club /data ‑viz
Training & Certifications
2021
Computational Systems Biology for Complex Human Disease
Wellcome Genome Campus Advanced Courses Cambridge, UK2019
NVIDIA-DIRAC AI Bootcamp
University College London University College London, UK2019
Data Visualisation for Biology
European Bioinformatics Institute (EMBL-EBI) Cambridge, UK2018
Statistical Analysis of Genetic Association Studies
University of Liverpool Liverpool, UK2018
Exploring Human Genetic Variation
European Bioinformatics Institute (EMBL-EBI) Cambridge, UK2018
Understanding the genetic architecture of complex traitst through SNP-based heritability analysis
University College London University College London, UK2017
Genetic Association Studies and Mendelian Randomization
University College London University College London, UKTalks
London, UK
Population-scale proteogenomic analysis identifies potential new
therapeutic targets for heart failure European Society of Cardiology Congress2024
- Presented in moderated poster session
2023
Genetic analysis in 1.9 million individuals reveals new insights into genetic variation underlying heart failure susceptibility
European Society of Human Genetics Conference Glasgow, UK- Presented in oral session
2020
Estimating the causal associations between plasma proteins and heart failure using Mendelian randomization
Workshop: Accelerating Precision Medicine with data science Örsundsbro, Sweden- Invited and sponsored by Olink Proetomics
2019
Large-scale genome-wide association study of heart failure identifies novel susceptibility loci and provides a platform for drug target validation
EMBL Conference: Target Validation Using Genomics and Informatics Heidelberg, Germany- Presented in poster session
2019
Sleep duration and cognition: Application of linear and non-linear Mendelian randomization in UK Biobank
South England Genetic Epidemiology Group (SEGEG) meeting Oxford, UKOther activities
current2019
UCL Code Clubs
University College London, UK- Co-lead of UCL Code Clubs, a volunteer-led group based at UCL aiming to introduce and encourage good coding practice and reproducibility in computational research
2021
The IHI Code Club Hackathon 2020+1
Institute of Health Informatics University College London, UK- Co-organise the IHI Code Club Hackathon 2020+1, a 3-day virtual collaborative public hackathon event to solve real-world issues in health data science
Grants & Awards
2024
American Heart Association Scientific Sessions 2024
Chicago, IL, USA- Paul Dudley White International Scholar Award for highest ranked abstract from United Kingdom
2023
American Heart Association Scientific Sessions 2023
Philadelphia, PA, USA- Paul Dudley White International Scholar Award for highest ranked abstract from United Kingdom
2023
American Society of Human Genetics Annual Meeting 2023
Washington D.C., USA- ASHG Trainee Research Excellence Award Winner (predoctoral category)
2023
Indonesian Society of Human Genetics Annual Meeting 2023
Makassar, Indonesia- Best oral presentation
2022
UCL Access and Widening Participation Bespoke Project Awards
University College London, UK- £3000 funding for ‘One Data Science’ project: introducing data science and statistics to A-level students across the UK
2021
UCL eResearch Community-Based Initiatives 2021
University College London, UK- £500 funding for UCL Code Clubs
2020
UCL eResearch Community-Based Initiatives 2020
University College London, UK- £500 funding for UCL Code Clubs
2020
UCL Researcher-led Initiatives 2020
University College London, UK- £1000 funding for IHI Code Club Hackathon
2020
London Genetics Network inaugural meeting 2020
London, UK- Best poster
- Poster title: Mendelian randomization analysis of circulating protein levels for therapeutic target prioritization in heart failure
2017
Alzheimer’s Indonesia conference 2017
Jakarta, Indonesia- Best poster
- Poster title: How sleep genes affect cognition – a Mendelian randomization study in UK Biobank
Selected Publications
2023
Genetic analysis in 1.9 million individuals provides insights into the causal aetiology underlying heart failure subtypes
Nature Genetics (manuscript in press)- Albert Henry, et al.
2023
Large-scale genome-wide association study of dilated cardiomyopathy in over one million participants identifies genes, pathways, and cellular communications contributing to pathology
Nature Genetics (manuscript in press)- Sean Zheng, Albert Henry (joint first author), et al.
2023
Druggable proteins influencing cardiac structure and function: Implications for heart failure therapies and cancer cardiotoxicity
Science Advances- Amand F Schmidt, …, Albert Henry, …, Jessica van Setten, Chris Finan
2023
The relationship between adiposity and cognitive function: a bidirectional Mendelian randomization study in UK Biobank
International Journal of Epidemiology- Tom Norris, Antoine Salzmann, Albert Henry, Victoria Garfield, Snehal M Pinto Pereira
2023
Identifying and visualising multimorbidity and comorbidity patterns in patients in the English National Health Service: a population-based study
The Lancet Digital Health- Valerie Kuan, …, Albert Henry, …, Harry Hemingway, Aroon D Hingorani
2022
Coupled myovascular expansion directs cardiac growth and regeneration
Development- Paige DeBenedittis, Anish Karpurapu, Albert Henry, …, R Thomas Lumbers, Ravi Karra
2022
Therapeutic targets for heart failure identified using proteomics and Mendelian randomization
Circulation- Albert Henry, María Gordillo-Marañón, Chris Finan, Amand F Schmidt, …, R Thomas Lumbers
2021
The genomics of heart failure: design and rationale of the HERMES consortium
ESC Heart Failure- R Thomas Lumbers, Sonia Shah, Honghuang Lin, Tomasz Czuba, Albert Henry, Daniel I Swerdlow, …
2021
Estimating the effect of reduced attendance at emergency departments for suspected cardiac conditions on cardiac mortality during the COVID-19 pandemic
Circulation: Cardiovascular Quality and Outcomes- Michail Katsoulis, Manuel Gomes, Alvina G Lai, Albert Henry, Spiros Denaxas, Pagona Lagiou, Vahe Nafilyan, Ben Humberstone, Amitava Banerjee, Harry Hemingway, R Thomas Lumbers
2021
Life-Time Covariation of Major Cardiovascular Diseases: A 40-Year Longitudinal Study and Genetic Studies
Circulation: Genomic and Precision Medicine- Lars Lind, Johan Sundström, Johan Ärnlöv, Martin Ingelsson, Albert Henry, R Thomas Lumbers, Erik Lampa
2020
Genetic and functional insights into the fractal structure of the heart
Nature- Hannah V Meyer, … Albert Henry …, Ewan Birney, Declan P O’Regan
2020
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure
Nature Communications- Sonia Shah, Albert Henry (joint first authors), …, R. Thomas Lumbers
2019
The relationship between sleep duration, cognition and dementia: a Mendelian randomization study
International Journal of Epidemiology- Albert Henry, Michail Katsoulis, Stefano Masi, Ghazaleh Fatemifar, Spiros Denaxas, Dionisio Acosta, Victoria Garfield, Caroline E Dale